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Propanamide, 2-hydroxy-

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Name

Propanamide, 2-hydroxy-

EINECS 218-049-3
CAS No. 2043-43-8 Density 1.161 g/cm3
PSA 63.32000 LogP -0.44720
Solubility N/A Melting Point 73-76 °C
Formula C3H7NO2 Boiling Point 281.9 °C at 760 mmHg
Molecular Weight 89.0941 Flash Point 124.3 °C
Transport Information N/A Appearance N/A
Safety 22-24/25 Risk Codes N/A
Molecular Structure Molecular Structure of 2043-43-8 (Lactamide) Hazard Symbols N/A
Synonyms

Lactamide(6CI,7CI,8CI);2-Hydroxypropionamide;DL-Lactamide;Lactic acid amide;Lactic amide;NSC 9903;

Article Data 44

Propanamide, 2-hydroxy- Specification

The Propanamide, 2-hydroxy-, with the CAS registry number 2043-43-8, is also known as Lactamide. Its EINECS registry number is 218-049-3. This chemical's molecular formula is C3H7NO2 and molecular weight is 89.09. What's more, both its IUPAC name and systematic name are the same which is called 2-Hydroxypropanamide.

Physical properties about Propanamide, 2-hydroxy- are: (1) ACD/LogP: -1.68; (2) # of Rule of 5 Violations: 0; (3) ACD/LogD (pH 5.5): -1.68; (4) ACD/LogD (pH 7.4): -1.68; (5) ACD/BCF (pH 5.5): 1; (6) ACD/BCF (pH 7.4): 1; (7) ACD/KOC (pH 5.5): 2.9; (8) ACD/KOC (pH 7.4): 2.9; (9) #H bond acceptors: 3; (10) #H bond donors: 3; (11) #Freely Rotating Bonds: 2; (12) Polar Surface Area: 29.54 Å2; (13) Index of Refraction: 1.459; (14) Molar Refractivity: 21 cm3; (15) Molar Volume: 76.7 cm3; (16) Surface Tension: 45.8 dyne/cm; (17) Density: 1.161 g/cm3; (18) Flash Point: 124.3 °C; (19) Enthalpy of Vaporization: 60.44 kJ/mol; (20) Boiling Point: 281.9 °C at 760 mmHg; (21) Vapour Pressure: 0.000409 mmHg at 25 °C; (22) Melting Point: 73-76 °C.

Preparation of Propanamide, 2-hydroxy-: this chemical can be prepared by 2-Hydroxy-propionitrile. This reaction needs reagent HCl and solvent Propan-2-ol.



Uses of Propanamide, 2-hydroxy-: it is used to produce other chemicals. For example, it is used to produce Pyruvamide. The reaction occurs with reagent Sodium dichromate, Sulphuric acid and solvent H2O, Acetone at temperature of 20 °C for 30 minutes. The yield is 51 %.



When you are dealing with this chemical, you should be very careful. The gas of this chemical can not be breathed. You should avoid contacting with skin and eyes.

You can still convert the following datas into molecular structure:
(1) SMILES: O=C(N)C(O)C
(2) InChI: InChI=1/C3H7NO2/c1-2(5)3(4)6/h2,5H,1H3,(H2,4,6)
(3) InChIKey: SXQFCVDSOLSHOQ-UHFFFAOYAP

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