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Propanamide,2-hydroxy-N-(2-hydroxyethyl)-

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Name

Propanamide,2-hydroxy-N-(2-hydroxyethyl)-

EINECS 226-546-1
CAS No. 5422-34-4 Density 1.184 g/cm3
PSA 69.56000 LogP -1.13340
Solubility Very soluble in water; insoluble in pentane and diethyl ether Melting Point N/A
Formula C5H11NO3 Boiling Point 380.3 °C at 760 mmHg
Molecular Weight 133.147 Flash Point 183.8 °C
Transport Information N/A Appearance Viscous, brownish liquid; Cooked brown roasted aroma
Safety 26-36/37/39 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 5422-34-4 (N-(2-HYDROXYETHYL)LACTAMIDE) Hazard Symbols N/A
Synonyms

Lactamide,N-(2-hydroxyethyl)- (6CI,7CI,8CI);Incromectant LMEA;Lactamide MEA;Lacticacid monoethanolamide;Lipamide LMEA;N-(2-Hydroxyethyl)lactamide;N-(b-Hydroxyethyl)-2-hydroxypropionamide;N-(b-Hydroxyethyl)lactamide;NSC11062;

 

Propanamide,2-hydroxy-N-(2-hydroxyethyl)- Specification

The Propanamide,2-hydroxy-N-(2-hydroxyethyl)-, with the CAS registry number 5422-34-4, is also known as N-(beta-Hydroxyethyl)-2-hydroxypropionamide. Its EINECS registry number is 226-546-1. This chemical's molecular formula is C5H11NO3 and molecular weight is 133.15. Its IUPAC name is called 2-hydroxy-N-(2-hydroxyethyl)propanamide. This chemical's classification codes are Drug / Therapeutic Agent; Mutation data.

Physical properties of Propanamide,2-hydroxy-N-(2-hydroxyethyl)-: (1)ACD/LogP: -1.61; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -1.61; (4)ACD/LogD (pH 7.4): -1.61; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 3.19; (8)ACD/KOC (pH 7.4): 3.19; (9)#H bond acceptors: 4; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 5; (12)Index of Refraction: 1.478; (13)Molar Refractivity: 31.86 cm3; (14)Molar Volume: 112.3 cm3; (15)Surface Tension: 47.4 dyne/cm; (16)Density: 1.184 g/cm3; (17)Flash Point: 183.8 °C; (18)Enthalpy of Vaporization: 72.69 kJ/mol; (19)Boiling Point: 380.3 °C at 760 mmHg; (20)Vapour Pressure: 2.4E-07 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Whenever you will contact it, please wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: CC(C(=O)NCCO)O
(2)InChI: InChI=1S/C5H11NO3/c1-4(8)5(9)6-2-3-7/h4,7-8H,2-3H2,1H3,(H,6,9)
(3)InChIKey: RZCHTMXTKQHYDT-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 16300mg/kg (16300mg/kg) CARDIAC: OTHER CHANGES

VASCULAR: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 1579, 1978.
mouse LD50 subcutaneous 23600mg/kg (23600mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 9, Pg. 711, 1959.
rat LD50 subcutaneous 24gm/kg (24000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 9, Pg. 711, 1959.

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