The Rabeprazole, with the CAS registry number 117976-89-3, has the systematic name of 2-({[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methyl}sulfinyl)-1H-benzimidazole. Its classification code are: Anti-Ulcer Agents; Enzyme Inhibitors; Gastrointestinal Agents. The molecular formula of this chemical is C₁₈H₂₁N₃O₃S.

The physical properties of Rabeprazole are as following: (1)ACD/LogP: 1.83; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.79; (4)ACD/LogD (pH 7.4): 1.82; (5)ACD/BCF (pH 5.5): 13.1; (6)ACD/BCF (pH 7.4): 14.29; (7)ACD/KOC (pH 5.5): 213.27; (8)ACD/KOC (pH 7.4): 232.59; (9)#H bond acceptors: 6; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 8; (12)Polar Surface Area: 85.45 Å²; (13)Index of Refraction: 1.654; (14)Molar Refractivity: 98.66 cm³; (15)Molar Volume: 268.9 cm³; (16)Polarizability: 39.11×10^-24cm³; (17)Surface Tension: 72.6 dyne/cm; (18)Density: 1.33 g/cm³; (19)Flash Point: 319.1 °C; (20)Enthalpy of Vaporization: 89.82 kJ/mol; (21)Boiling Point: 603.9 °C at 760 mmHg; (22)Vapour Pressure: 1.54E-14 mmHg at 25°C.

Preparation of Rabeprazole: Dissolve 2-[[[3-methyl-4-(3-methoxy-propoxy)-2-pyridyl]methyl]thio]-1H-benzimidazole in the methylene dichloride, and add m-chloroperoxybenzoic acid of dichloromethane. Then deal it with sodium hydroxide, methylene chloride, ammonia and acetone, the aim product is obtained.

Uses of Rabeprazole: It is a proton pump antagonist, and inhibits urease. It is used for the short-term treatment in healing and symptomatic relief of duodenal ulcers and erosive or ulcerative gastroesophageal reflux disease (GERD). It is used for maintaining healing and reducing relapse rates of heartburn symptoms in patients with GERD; It is also used in the treatment of daytime and nighttime heartburn and other symptoms associated with GERD; In addition, it is used for long-term treatment of pathological hypersecretory conditions as well.

You should be cautious while dealing with this chemical. It irritates eyes and skin. Therefore, you had better take the following instructions: Wear suitable gloves and eye/face protection, and in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: O=S(c2nc1ccccc1n2)Cc3nccc(OCCCOC)c3C
(2)InChI: InChI=1/C18H21N3O3S/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18/h3-4,6-9H,5,10-12H2,1-2H3,(H,20,21)
(3)InChIKey: YREYEVIYCVEVJK-UHFFFAOYAY