- Ranolazine
- Ranolazine dihydrochloride
- 95635-56-61-Piperazineacetamide,N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-, hydrochloride(1:2)
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Cas Database |
| Name |
Ranolazine |
EINECS | 620-450-7 |
| CAS No. | 95635-55-5 | Density | 1.174 g/cm3 |
| PSA | 74.27000 | LogP | 2.25680 |
| Solubility | N/A | Melting Point |
119-1200C |
| Formula | C24H33N3O4 | Boiling Point | 624.1 °C at 760 mmHg |
| Molecular Weight | 427.544 | Flash Point | 331.2 °C |
| Transport Information | N/A | Appearance | white solid |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-;( -)-Ranolazine;Ran4;RS-43285-003;N-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide;Ranexa;1-[3-(2-methoxyphenoxy)-2-hydroxypropyl]-4-[(2,6-dimethylphenyl)aminocarbonylmethy]piperazine;1-[3-(2-methoxyphenoxy)-2-hydroxypropyl]-4-[...;1-Piperazineacetamide,N-(2,6-dimethylphenyl)- 4-[2-hydroxy-3-(2-methoxyphenoxy)- propyl]-;N-(2,6-dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamide; |
Article Data | 19 |
Ranolazine Chemical Properties
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IUPAC Name: N-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide
Molecular Formula: C24H33N3O4
Molecular Weight: 427.54 g/mol
Canonical SMILES: CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)C(COC3=CC=CC=C3OC)O
InChI: InChI=1S/C24H33N3O4/c1-18-7-6-8-19(2)24(18)25-23(29)16-27-13-11-26(12-14-27)15-20(28)17-31-22-10-5-4-9-21(22)30-3/h4-10,20,28H,11-17H2,1-3H3,(H,25,29)
Classification Code: Enzyme Inhibitors; Partial Fatty Acid Oxidation (pFOX) Inhibitors; anti-anginal; anti-ischemic
Product Categories: APIs; Antianginal; API; Aromatics; Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals
Index of Refraction: 1.585
Molar Refractivity: 122.14 cm3
Molar Volume: 364 cm3
Polarizability: 48.42×10-24 cm3
Surface Tension: 49.4 dyne/cm
Density: 1.174 g/cm3
Flash Point: 331.2 °C
Enthalpy of Vaporization: 97.15 kJ/mol
Boiling Point: 624.1 °C at 760 mmHg
Vapour Pressure of Ranolazine (CAS NO.95635-55-5): 1.94E-16 mmHg at 25 °C
Ranolazine Uses
Ranolazine (CAS NO.95635-55-5) is applicated for the treatment of Chronic angina. It decreases angina episodes in individuals with coronary artery disease on maximal doses of amlodipine.It also decreases both angina episodes and increase exercise tolerance in individuals taking concomitant atenolol, amlodipine, or diltiazem.
Ranolazine Safety Profile
The most common adverse events of Ranolazine are dizziness, nausea, constipation, fatigue.
Ranolazine Specification
Ranolazine (CAS NO.95635-55-5), its Synonyms are 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-(2-hydroxy-
3-(2-methoxyphenoxy)propyl)- ; ( -)-Ranolazine ; (+-)-N-(2,6-Dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-1-piperazineacetamide ; 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-, (+-)- ; Ranexa . It is white solid.
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