Products Categories
| CAS No.: | 2210-74-4 |
|---|---|
| Name: | Guaiacol glycidyl ether |
| Molecular Structure: | |
|
|
|
| Formula: | C10H12O3 |
| Molecular Weight: | 180.203 |
| Synonyms: | Benzene,1-(2,3-epoxypropoxy)-2-methoxy- (6CI,7CI,8CI);Oxirane,[(2-methoxyphenoxy)methyl]- (9CI);1,2-Epoxy-3-(2-methoxyphenoxy)propane;1,2-Epoxy-3-(o-methoxyphenoxy)propane;1-(2-Methoxyphenoxy)-2,3-epoxypropane;2-(2,3-Epoxypropoxy)anisole;2-Methoxy-1-(oxiranylmethoxy)benzene;2-Methoxyphenyl glycidyl ether;2-[(2-Methoxyphenoxy)methyl]oxirane;Glycidyl2-methoxyphenyl ether;NSC 112256;NSC 133442; |
| EINECS: | 218-644-8 |
| Density: | 1.142 g/cm3 |
| Melting Point: | 33-36 °C |
| Boiling Point: | 265.3 °C at 760 mmHg |
| Flash Point: | 87.4 °C |
| Solubility: | 4.21g/L at 20℃ |
| Appearance: | White crystalline solid |
| PSA: | 30.99000 |
| LogP: | 1.47280 |
- 483366-12-7(2S,4R)-1-Boc-2-cyano-4-hydroxypyrrolidine
- 361456-36-2METHYL (R)-(+)-ISOCYANATO-3-PHENYLPROPI&
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 240444-70-62,3,5,6-Tetrafluor-4-(methoxymethyl)benzyl-2,2-dimethyl-3-(prop-1-en-1-yl)cyclopropancarboxylat
- 68439-39-4Poly(oxy-1,2-ethanediyl), alpha-(2-ethylhexyl)-omega-hydroxy-,
- 13052-77-2
sodium 2-methoxyphenolate
- 106-89-8
epichlorohydrin
- 2210-74-4
2-(2-methoxy-phenoxymethyl)-oxirane
| Conditions | Yield |
|---|---|
| at 20℃; for 24h; | 95% |
| Conditions | Yield |
|---|---|
| Stage #1: 2-methoxy-phenol With sodium hydroxide In water at 30℃; Large scale; Stage #2: epichlorohydrin In water at 25 - 35℃; Large scale; | 94% |
| With potassium carbonate at 120℃; for 4.5h; | 93% |
| With n-Bu4NOSO2OCH2CHOHCH3; potassium carbonate at 75 - 80℃; for 1h; | 90% |
- 90-05-1
2-methoxy-phenol
- 3132-64-7
1,2-Epoxy-3-bromopropane
- 2210-74-4
2-(2-methoxy-phenoxymethyl)-oxirane
| Conditions | Yield |
|---|---|
| With potassium carbonate In tetrahydrofuran Heating; | 82% |
| With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 6h; | 62% |
| With base | |
| With potassium carbonate In butanone at 80℃; |
- 90-05-1
2-methoxy-phenol
- 106-89-8
epichlorohydrin
A
- 25772-81-0
1-chloro-3-(2-methoxyphenoxy)-2-propyl alcohol
B
- 2210-74-4
2-(2-methoxy-phenoxymethyl)-oxirane
| Conditions | Yield |
|---|---|
| With sodium hydroxide In water for 7h; Heating; | A 23% B 68% |
| With sodium hydroxide In 1,4-dioxane; water at 25 - 30℃; | |
| With sodium hydroxide at 25 - 30℃; |
| Conditions | Yield |
|---|---|
| With diethyl ether |
| Conditions | Yield |
|---|---|
| With sodium hydroxide | |
| With sodium hydroxide |
| Conditions | Yield |
|---|---|
| tris-(3,6-dioxa-octyl)amine In acetonitrile |
- 90-05-1
2-methoxy-phenol
- 106-89-8
epichlorohydrin
A
- 16929-60-5
1,3-bis(2-methoxyphenoxy)propan-2-ol
B
- 2210-74-4
2-(2-methoxy-phenoxymethyl)-oxirane
| Conditions | Yield |
|---|---|
| Stage #1: 2-methoxy-phenol With sodium hydroxide; tetrabutylammomium bromide In water; toluene at 25 - 30℃; for 0.5h; Stage #2: epichlorohydrin In water; toluene at 35 - 40℃; for 6h; Product distribution / selectivity; | |
| With sodium hydroxide at 10 - 15℃; Temperature; |
- 90-05-1
2-methoxy-phenol
- 106-89-8
epichlorohydrin
A
- 25772-81-0
1-chloro-3-(2-methoxyphenoxy)-2-propyl alcohol
B
- 16929-60-5
1,3-bis(2-methoxyphenoxy)propan-2-ol
C
- 93-14-1
guaifenesin
D
- 2210-74-4
2-(2-methoxy-phenoxymethyl)-oxirane
| Conditions | Yield |
|---|---|
| With sodium hydroxide In toluene at 25 - 30℃; Solvent; Concentration; |
| Conditions | Yield |
|---|---|
| at 20℃; | 99% |
What can I do for you?
Get Best Price
Chemistry
IUPAC Name: 2-[(2-Methoxyphenoxy)methyl]oxirane
Following is the structure of Oxirane,2-[(2-methoxyphenoxy)methyl]- (CAS NO.2210-74-4):
Empirical Formula: C10H12O3
Molecular Weight: 180.2005
EINECS: 218-644-8
Index of Refraction: 1.526
Molar Refractivity: 48.45 cm3
Molar Volume: 157.7 cm3
Density: 1.142 g/cm3
Flash Point: 87.4 °C
Melting point: 33-36 °C
Polarizability: 19.2 10-24cm3
Surface Tension: 40.4 dyne/cm
Enthalpy of Vaporization: 48.29 kJ/mol
Boiling Point: 265.3 °C at 760 mmHg
Vapour Pressure: 0.0152 mmHg at 25 °C
Appearance of Oxirane,2-[(2-methoxyphenoxy)methyl]- (CAS NO.2210-74-4): White Crystalline Solid
Product Categories: INTERMEDIATESOFRANOLAZINE; API intermediates; Various Intermediates; Intermediates; Intermediates & Fine Chemicals; Pharmaceuticals; Ranolazine
Canonical SMILES: COC1=CC=CC=C1OCC2CO2
InChI: InChI=1S/C10H12O3/c1-11-9-4-2-3-5-10(9)13-7-8-6-12-8/h2-5,8H,6-7H2,1H3
InChIKey: RJNVSQLNEALZLC-UHFFFAOYSA-N
Uses
Oxirane,2-[(2-methoxyphenoxy)methyl]- (CAS NO.2210-74-4) can be used as Ranolazine intermediate.
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | subcutaneous | 1355mg/kg (1355mg/kg) | BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) | Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 1355, 1965. |
Specification
Oxirane,2-[(2-methoxyphenoxy)methyl]- , its cas register number 2210-74-4. It also can be called 1,2-Epoxy-3-(o-methoxyphenoxy)propane ; Guajacol-glycidaether ; Guajacol-glycidaether [German] ; NSC 112256 ; NSC 133442 ; and Propane, 1,2-epoxy-3-(o-methoxyphenoxy)- .