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Name |
Rizatriptan |
EINECS | N/A |
CAS No. | 144034-80-0 | Density | 1.21 g/cm3 |
PSA | 49.74000 | LogP | 1.91180 |
Solubility | water: 42 mg/mL | Melting Point |
178-180 °C |
Formula | C15H19N5 | Boiling Point | 504.8 °C at 760 mmHg |
Molecular Weight | 269.349 | Flash Point | 259.1 °C |
Transport Information | N/A | Appearance | N/A |
Safety | Risk Codes | N/A | |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
3-[2-(Dimethylamino)ethyl]-5-(1H-1,2,4-triazol-1-ylmethyl)indole;MK 462 free base;N,N-Dimethyl-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine;Risatriptan;Rizatriptan; |
Article Data | 21 |
Rizatriptan (144034-80-0) is a 5-HT1 agonist triptan drug developed by Merck & Co. for the treatment of migraine headaches. It is available in strengths of 5 and 10 mg as tablets and orally disintegrating tablets (Maxalt-MLT).
Maxalt obtained approval by the United States Food and Drug Administration (FDA) on June 29, 1998. It is a second-generation triptan.
Rizatriptan(144034-80-0) is available only by prescription in the United States, Canada and New Zealand. Similarly, it is classed as a POM (Prescription Only Medicine) in the United Kingdom, Italy (as Rizaliv) and Israel (as Rizalt).
The density of Rizatriptan(144034-80-0) is 1.21 g/cm3 and it has a melting point of 178-180°C. The boiling point is 504.8 °C at 760 mmHg. The refractive index is about 1.645. Its flash point is 259.1 °C.
The chemical synonyms of Rizatriptan(144034-80-0) are n,n-dimethyl-5-(1h-1,2,4-triazol-1-ylmethyl)-1h-indole-3-ethanamine;n,n-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1h-indol-3-yl]ethanamine;RIZATRIPTAN
The molecular structure of Rizatriptan(144034-80-0):