Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
Ronidazole |
EINECS | 231-675-1 |
CAS No. | 7681-76-7 | Density | 1.65 g/cm3 |
PSA | 115.96000 | LogP | 1.14710 |
Solubility | N/A | Melting Point |
167-169° |
Formula | C6H8N4O4 | Boiling Point | 502.3 °C at 760 mmHg |
Molecular Weight | 200.154 | Flash Point | 257.6 °C |
Transport Information | N/A | Appearance | N/A |
Safety | 22-24/25 | Risk Codes | N/A |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
1H-Imidazole-2-methanol,1-methyl-5-nitro-, carbamate (ester) (9CI);Imidazole-2-methanol,1-methyl-5-nitro-, carbamate (ester) (8CI);1-Methyl-2-carbamoyloxymethyl-5-nitroimidazole;Dugro;MCMN;Ridzol;Ridzol P;Ridzole;Ronida BT; |
Article Data | 15 |
(1-methyl-5-nitro-1H-imidazol-2-yl)methyl 4-nitrophenyl carbonate
ronidazole
Conditions | Yield |
---|---|
With ammonium hydroxide In dichloromethane at 0 - 10℃; for 3h; Inert atmosphere; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: triethylamine / dichloromethane / 20 °C / Inert atmosphere 2: ammonium hydroxide / dichloromethane / 3 h / 0 - 10 °C / Inert atmosphere View Scheme |
Conditions | Yield |
---|---|
In ethanol; acetone for 2.5h; Reflux; | 94% |
Conditions | Yield |
---|---|
In ethanol; acetone for 24h; Reflux; | 89% |
potassium tetrachloroplatinate(II)
ronidazole
(NO2CCHNC(CH2OC(O)NH2)N(CH3))2PtCl2
Conditions | Yield |
---|---|
In water solid ligand added to aq. soln. of K2(PtCl4), stirred at 50 °C for 1 h; ppt. filtered, washed with EtOH/Et2O, Et2O, dried in vac.; elem. anal.; | 81% |
Conditions | Yield |
---|---|
In ethanol; acetone for 2.5h; Reflux; | 81% |
Conditions | Yield |
---|---|
In ethanol; acetone for 4h; Reflux; | 78.86% |
Conditions | Yield |
---|---|
In ethanol; acetone for 24h; Reflux; | 78.67% |
Conditions | Yield |
---|---|
In ethanol; acetone for 4h; Reflux; | 76.86% |
Conditions | Yield |
---|---|
In ethanol; dichloromethane; acetone for 4h; Reflux; | 74.96% |
1. | mmo-sat 3 µg/plate | CBINA8 Chemico-Biological Interactions. 49 (1984),27. | ||
2. | mmo-smc 500 ppm | MUREAV Mutation Research. 86 (1981),243. | ||
3. | orl-rat LD50:3400 mg/kg | VMDNAV Veterinarno-Meditsinski Nauki. 22 (7)(1985),90. | ||
4. | ipr-rat LD50:1500 mg/kg | VMDNAV Veterinarno-Meditsinski Nauki. 22 (7)(1985),90. |