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Sodium chromate

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Sodium chromate

EINECS 231-889-5
CAS No. 7775-11-3 Density 2.72 g/cm3
PSA 80.26000 LogP -0.47520
Solubility soluble in water Melting Point 792 °C
Formula CrH2O4.2Na Boiling Point 392oC
Molecular Weight 163.97 Flash Point N/A
Transport Information UN 3288 6.1/PG 2 Appearance Yellow crystals or crystalline powder
Safety 53-45-60-61 Risk Codes 45-46-60-61-21-25-26-34-42/43-48/23-50/53
Molecular Structure Molecular Structure of 7775-11-3 (Sodium chromate) Hazard Symbols VeryT+,DangerousN
Synonyms

Chromicacid (H2CrO4), disodium salt (8CI,9CI);Chromium disodium oxide;Chromiumsodium oxide (CrNa2O4);Disodium chromate;Disodium chromate (Na2CrO4);Sodiumchromate;Sodium chromate (Na2(CrO4));Sodium chromate (VI);Sodium chromiumoxide (Na2CrO4);

 

Sodium chromate Consensus Reports

IARC Cancer Review: Group 1 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 49 , 1990,p. 49.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 23 , 1980,p. 205.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 49 , 1990,p. 49.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 23 , 1980,p. 205.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program. Chromium and its compounds are on the Community Right-To-Know List.

Sodium chromate Standards and Recommendations

OSHA PEL: Cl 0.1 mg(CrO3)/m3
ACGIH TLV: TWA 0.05 mg(CrO3)/m3
NIOSH REL: (Chromium(VI)) TWA 25 µg(Cr(VI))/m3; CL 50 µg/m3/15M

Sodium chromate Analytical Methods

For occupational chemical analysis use NIOSH: Chromium Hexavalent 7024.

Sodium chromate Specification

The Disodium chromate with CAS registry number of 7775-11-3 is also called Sodiumchromate. Its EINECS registry number is 231-889-5. The IUPAC name is disodium dioxido(dioxo)chromium. In addition, the molecular formula is CrH2O4.2Na and the molecular weight is 163.97. It is a kind of Yellow crystals or crystalline powder and belongs to the classes of Inorganics; Inorganic Salts; Salts; Sodium Salts; SodiumMetal and Ceramic Science; Synthetic Reagents.

Physical properties about this chemical are: (1)#H bond acceptors:4; (2)#H bond donors:2; (3)Polar Surface Area:74.6 ?2; (4)Exact Mass: 161.89971; (5)MonoIsotopic Mass: 161.89971; (6)Topological Polar Surface Area: 80.3; (7)Heavy Atom Count: 7; (8)Complexity: 62.2; (9)Covalently-Bonded Unit Count: 3.

Preparation of Disodium chromate: it can be prepared by chromite in the presence of strong oxidizing agents. The reaction temperature is 1100-1200 °C. The equation is as follows:

Disodium chromate can be prepared by chromite in the presence of strong oxidizing agents

Uses of Disodium chromate: it is mainly used as corrosion inhibitors for ink, paint and metal, and used as oxidant in organic synthesis. In addition, it is a kind of inhibitor for concrete admixtures.

When you are using this chemical, please be cautious about it as the following:
It has risk of explosion by shock, friction, fire or other sources of ignition. And it contact with combustible material may cause fire. It may cause sensitization by inhalation and skin contact. Besides, it has danger of serious damage to health by prolonged exposure through inhalation. And it is very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. In addition, it may cause cancer and heritable genetic damage. You should avoid exposure - obtain special instruction before use. During using it, in case of accident or if you feel unwell, seek medical advice immediately (show label where possible). This material and/or its container must be disposed of as hazardous waste. Moreover, you should avoid release to the environment. You can refer to special instructions safety data sheet.

You can still convert the following datas into molecular structure:
(1)SMILES: [Na+].[Na+].[O-][Cr]([O-])(=O)=O
(2)InChI: InChI=1/Cr.2Na.4O/q;2*+1;;;2*-1/rCrO4.2Na/c2-1(3,4)5;;/q-2;2*+1
(3)InChIKey: PXLIDIMHPNPGMH-JYQPEEMKAO

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 intravenous 164mg/kg (164mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Agressologie. Revue Internationale de Physio-Biologie et de Pharmacologie Appliquees aux Effets de l'Agression. Vol. 8, Pg. 51, 1967.
dog LDLo intravenous 235mg/kg (235mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
guinea pig LDLo intradermal 382mg/kg (382mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Anatomy and Physiology. Vol. 11, Pg. 285, 1877.
guinea pig LDLo intraperitoneal 206mg/kg (206mg/kg)   Archives of Environmental Health. Vol. 11, Pg. 201, 1965.
guinea pig LDLo skin 206mg/kg (206mg/kg)   Archives of Environmental Health. Vol. 11, Pg. 201, 1965.
guinea pig LDLo subcutaneous 30mg/kg (30mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
mouse LD50 intraperitoneal 32mg/kg (32mg/kg)   Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 257, Pg. 791, 1963.
rabbit LDLo intradermal 250mg/kg (250mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Anatomy and Physiology. Vol. 11, Pg. 285, 1877.
rabbit LDLo intravenous 32mg/kg (32mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rabbit LDLo subcutaneous 243mg/kg (243mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rat LD50 intraperitoneal 57mg/kg (57mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: COMA
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 154, Pg. 243, 1965.
rat LD50 oral 136mg/kg (136mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

CARDIAC: OTHER CHANGES

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
International Journal of Toxicology. Vol. 19, Pg. 338, 2000.

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