- Sophoridine
- Sophoridine
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Cas Database |
| Name |
Sophoridine |
EINECS | N/A |
| CAS No. | 83148-91-8 | Density | 1.16 g/cm3 |
| PSA | 23.55000 | LogP | 1.74750 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C15H24N2O | Boiling Point | 396.7 °C at 760 mmHg |
| Molecular Weight | 248.368 | Flash Point | 172.7 °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
(+)-Sophoridine;d-Sophoridine; |
Article Data | 2 |
Sophoridine Chemical Properties
Sophoridine(83148-91-8) is also called for Sophoridin ; l-Sophoridine ; Matrine ; 5-Epidihydrosophocarpine ; Dihydro-5-episophocarpine ; (5-beta)-Matridin-15-one ; (5beta)-Matridin-15-one ; Matridin-15-one, (5-beta)- (9CI) ; TL8004825 ; Bio-0637 and so on.
Molecular Formula: C15H24N2O
Molecular Weight: 248.36
Molar Volume: 213.3 cm3
Density: 1.16 g/cm3
Flash Point: 172.7°C
Boiling Point: 396.7°C at 760 mmHg
LogP: ACD/LogP: 1.44
LogP: 1.40
ACD/LogD (pH 5.5): -1.59
ACD/LogD (pH 7.4): -0.47
ACD/BCF (pH 5.5): 1
ACD/BCF (pH 7.4): 1
ACD/KOC (pH 5.5): 1
ACD/KOC (pH 7.4): 1.79
H bond acceptors: 3
H bond donors: 0
Freely Rotating Bonds: 0
Index of Refraction: 1.581
Molar Refractivity: 71.12 cm3
Surface Tension: 48.3 dyne/cm
Enthalpy of Vaporization: 64.71 kJ/mol
The molecular structure of Sophoridine(83148-91-8):
Sophoridine Uses
Sophoridine(83148-91-8) is used as a pharmaceutical composition that has analgetic effects and sophoridine which is an alkaloid and is derived from sophora alopecuroides L. When the sophoridine or its derivates or its analogs are used as analgesics, in addition to antitumor activity and analgetic effects of biquinolizidines compounds, they will have an advantage of not refraining from them after long term application.
Sophoridine Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 64300ug/kg (64.3mg/kg) | Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. Vol. 8, Pg. 153, 1987. | |
| mouse | LD50 | intravenous | 46800ug/kg (46.8mg/kg) | Yaowu Fenxi Zazhi. Journal of Pharmaceutical Analysis. Vol. 6, Pg. 96, 1986. | |
| mouse | LD50 | oral | 243mg/kg (243mg/kg) | Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. Vol. 27, Pg. 201, 1992. |
Sophoridine Specification
Treatment of Sophoridine(83148-91-8) in Wastewater, see as follows:
Total removal: 2.05 percent
Total biodegradation: 0.09 percent
Total sludge adsorption: 1.96 percent
Total to Air: 0.00 percent
(using 10000 hr Bio P,A,S)
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