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Spartocin

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Name

Spartocin

EINECS N/A
CAS No. 299-39-8 Density g/cm3
PSA 89.46000 LogP 2.64890
Solubility N/A Melting Point 135°C
Formula C15H26N2•H2O4S Boiling Point 340.9°Cat760mmHg
Molecular Weight 430.544 Flash Point 148.3°C
Transport Information N/A Appearance N/A
Safety Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human reproductive effects by intramuscular route: stillbirth; changes in uterus, cervix and vagina. When heated to decomposition it emits toxic fumes of NOx and SOx. Risk Codes 23/25-33
Molecular Structure Molecular Structure of 299-39-8 (SPARTEINE SULFATE) Hazard Symbols N/A
Synonyms

siarczansparteiny;spal;spareng;sparm;sparteal;spartepur;spartin;spartocin

Article Data 1

Spartocin Chemical Properties

Product Name: Sparteine sulfate
Synonyms: 7,14-Methano-2H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocine, dodecahydro-, (7S-(7alpha,7aalpha,14alpha,14abeta))-, sulfate (1:1) (9CI) ; L-Spartein sulfat ; Spal ; Spareng ; Sparm
CAS NO: 299-39-8
Molecular Formula of Spartocin (CAS NO.299-39-8) : C15H28N2O4S
Molecular Weight of Spartocin (CAS NO.299-39-8) : 332.46
Molecular Structure of Spartocin (CAS NO.299-39-8) :
EINECS: 206-078-4
Flash Point: 148.3 °C
Enthalpy of Vaporization: 58.45 kJ/mol
Boiling Point: 340.9 °C at 760 mmHg
Vapour Pressure: 8.34E-05 mmHg at 25°C
Melting point: 135°C

Spartocin Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
frog LDLo parenteral 375mg/kg (375mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 27, Pg. 431, 1926.
guinea pig LDLo intraperitoneal 42mg/kg (42mg/kg)   Journal of Agricultural Research Vol. 32, Pg. 51, 1926.
mouse LD50 intraperitoneal 43mg/kg (43mg/kg)   Journal of Medicinal Chemistry. Vol. 20, Pg. 1668, 1977.
mouse LD50 intravenous 15mg/kg (15mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: STIFFNESS

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Japanese Journal of Pharmacology. Vol. 16, Pg. 353, 1966.
mouse LD50 oral 350mg/kg (350mg/kg) BEHAVIORAL: EXCITEMENT Arzneimittel-Forschung. Drug Research. Vol. 30, Pg. 1497, 1980.
mouse LD50 subcutaneous 117mg/kg (117mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: STIFFNESS

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Japanese Journal of Pharmacology. Vol. 16, Pg. 353, 1966.
rabbit LDLo subcutaneous 80mg/kg (80mg/kg) VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION Journal of Pharmacology and Experimental Therapeutics. Vol. 27, Pg. 431, 1926.
rat LD50 intravenous 30400ug/kg (30.4mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: STIFFNESS

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Japanese Journal of Pharmacology. Vol. 16, Pg. 353, 1966.

Spartocin Safety Profile

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human reproductive effects by intramuscular route: stillbirth; changes in uterus, cervix and vagina. When heated to decomposition it emits toxic fumes of NOx and SOx.
Risk Statements 23/25-33
R23/25:Toxic by inhalation and if swallowed. 
R33:Danger of cumulative effects.
Safety Statements 1-45
S1 :Keep locked up. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR 1544
HazardClass 6.1(b)
PackingGroup III

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