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Molecular Structure:
Molecular Formula: OTl2
Molecular Weight: 424.766
IUPAC Name: $l^{1}-Thallanyloxythallium
Synonyms of Thallium oxide (CAS NO.1314-12-1): Dithallium oxide ; Thallium oxide (Tl2O)
CAS NO: 1314-12-1
EINECS: 215-220-4
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LDLo | intraperitoneal | 31200ug/kg (31.2mg/kg) | BRAIN AND COVERINGS: ENCEPHALITIS GASTROINTESTINAL: OTHER CHANGES SKIN AND APPENDAGES (SKIN): HAIR: OTHER | "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978Vol. 2, Pg. 101, 1978. |
dog | LDLo | oral | 31200ug/kg (31.2mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: OTHER CHANGES BLOOD: HEMORRHAGE | "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978Vol. 2, Pg. 101, 1978. |
rabbit | LDLo | intraperitoneal | 62400ug/kg (62.4mg/kg) | BRAIN AND COVERINGS: ENCEPHALITIS GASTROINTESTINAL: OTHER CHANGES SKIN AND APPENDAGES (SKIN): HAIR: OTHER | "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978Vol. 2, Pg. 101, 1978. |
rabbit | LDLo | intravenous | 40600ug/kg (40.6mg/kg) | BRAIN AND COVERINGS: ENCEPHALITIS SKIN AND APPENDAGES (SKIN): HAIR: OTHER GASTROINTESTINAL: OTHER CHANGES | "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978Vol. 2, Pg. 101, 1978. |
rabbit | LDLo | oral | 31200ug/kg (31.2mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: OTHER CHANGES BLOOD: HEMORRHAGE | "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978Vol. 2, Pg. 101, 1978. |
rat | LD50 | intraperitoneal | 75mg/kg (75mg/kg) | BRAIN AND COVERINGS: ENCEPHALITIS GASTROINTESTINAL: OTHER CHANGES SKIN AND APPENDAGES (SKIN): HAIR: OTHER | "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978Vol. 2, Pg. 101, 1978. |
rat | LD50 | oral | 40600ug/kg (40.6mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: OTHER CHANGES BLOOD: HEMORRHAGE | "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978Vol. 2, Pg. 101, 1978. |
Reported in EPA TSCA Inventory.
Poison by ingestion, intraperitoneal, and intravenous routes. When Thallium oxide (CAS NO.1314-12-1) is heated to decomposition, it emits toxic vapors of Tl.
RIDADR: 1707
HazardClass: 6.1(a)
PackingGroup: II