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Name |
Thyroid |
EINECS | N/A |
CAS No. | 50809-32-0 | Density | N/A |
PSA | 95.61000 | LogP | 3.92290 |
Solubility | N/A | Melting Point |
N/A |
Formula | Unspecified | Boiling Point | N/A |
Molecular Weight | 798.85200 | Flash Point | N/A |
Transport Information | N/A | Appearance | N/A |
Safety | Risk Codes | N/A | |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
THYROID LYOPHILIZED;THYROID USP;Thyroid Powder;THYROID;Available CAS No. 55-03-8;WHDH; |
IUPAC Name: Sodium(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate
Molecular Weight: 798.85185 g/mol
Molecular Formula: C15H10I4NNaO4
H-Bond Donor: 2
H-Bond Acceptor: 5
Rotatable Bond Count: 5
Tautomer Count: 2
Exact Mass: 798.668624
MonoIsotopic Mass: 798.668624
Topological Polar Surface Area: 95.6
Heavy Atom Count: 25
Complexity: 426
Defined Atom StereoCenter Count: 1
InChI: InChI=1S/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/q;+1/p-1/t12-;/m0./s1
InChIKey: YDTFRJLNMPSCFM-YDALLXLXSA-M
Product Categories: Protein Extracts; Acetone Powders; Biochemicals and Reagents; Proteins and Derivatives
Storage temp.: 2-8 °C
Flash Point: 302.3 °C
Enthalpy of Vaporization: 90.78 kJ/mol
Boiling Point: 576.3 °C at 760 mmHg
Vapour Pressure of Thyroid (CAS NO.50809-32-0): 4.02E-14 mmHg at 25 °C
In the Medieval Medical School of Salerno (XII Century), there are several findings that evidence a great interest for thyroid disorders. Rogerius Salernitanus, the Salernitan surgeon and author of "Post mundi fabricam" (around 1180) was considered at that time the surgical text par excellence all over Europe. In the chapter "De bocio" of his magnum opus he describes several pharmacological and surgical cures, some of which nowadays are reappraised quite scientifically effective. In 1656, the Thyroid (CAS NO.50809-32-0) was first identified by the anatomist Thomas Wharton whose name is also eponymised in Wharton's duct of the submandibular gland. Thyroxin was identified only in the 19th century.
Thyroid (CAS NO.50809-32-0) controls how quickly the body burns energy, makes proteins, and it also controls how sensitive the body should be to other hormones.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
child | TDLo | oral | 291mg/kg (291mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: IRRITABILITY | New England Journal of Medicine. Vol. 256, Pg. 459, 1957. |
women | TDLo | oral | 48gm/kg/26W-I (48000mg/kg) | CARDIAC: CARDIOMYOPATHY INCLUDING INFARCTION LUNGS, THORAX, OR RESPIRATION: DYSPNEA SKIN AND APPENDAGES (SKIN): SWEATING: OTHER | Archives of Internal Medicine. Vol. 148, Pg. 1450, 1988. |
An experimental teratogen. Human systemic effects by ingestion: cardiomyopathy, dyspnea, and sweating. When heated to decomposition it emits acrid smoke and irritating fumes.
WGK Germany: 3
RTECS XP: 3575000
Synonyms of Thyroid (CAS NO.50809-32-0) are Porcine ; Thyroid powder porcine ; Thyradin ; Thyroid powder porcine grade i ; Thyroid powder porcine grade iii ; Thyroid lyophilized, from porcine .