20S proteasome

A large protein complex responsible for degrading unneeded or damaged proteins in the cell

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A new structural class of selective and non-covalent inhibitors of the chymotrypsin-like activity of the 20S proteasome
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Phenoxypropanolamine derivatives as selective inhibitors of the 20S proteasome β1 and β5 subunits
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Molecular docking Apoptosis Selective Inhibitors Structure-Activity Relationship (SAR) Enzyme Kinetics High-Throughput Screening (HTS) Experimental terms Cell viability assay Structural class IC50 (Half-Maximal Inhibitory Concentration) Western blot MICHAELIS-MENTEN KINETICS Phenoxypropanolamine derivatives

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