HTS involves testing a large number of compounds for their ability to block potassium channels in a relatively short amount of time. Automation and robotics are often used to speed up this process.
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1-[5-(2-Fluoropyridin-3-yl)-1-(phenylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate
(2S)-cyclohexyl({[5-(2,6-dimethoxyphenyl)-1-(4-fluorophenyl)-1H-pyrazol-3-yl]carbonyl}amino)ethanoic acid
methyl 3-(4-((2-chloropyridin-4-yl)ethynyl)phenyl)propanoate
4-(bromomethyl)-N-cyclohexyl-N-methylbenzenesulfonamide
12
(S)-2-TERT-BUTOXYCARBONYLAMINO-3-NAPHTHALEN-2-YL-PROPIONIC ACID METHYL ESTER
methyl 3-{N-(1-butyl)-2-chloro-4-{[3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl]methoxy}benzamido}benzoate
2-(2-fluorobiphenyl-4-yl)-6-phenylimidazo[2,1-b][1,3,4]thiadiazole
5-chloro-N4-methyl-N2-phenylpyrimidine-2,4-diamine
[4-(2-benzyloxy-4-fluoro-phenyl)-2,6-diisopropyl-5-vinyl-pyridin-3-yl]-methanol
(S)-tert-butyl 1-(3-aminopyridin-4-yl)piperidin-3-ylcarbamate
1-cyclopropyl-3-(4-(5-(2,2-difluoropropyl)-6a-methyl-6-oxo-5,6,6a,7,9,10-hexahydro[1,4]oxazino[3,4-h]pteridin-2-yl)phenyl)urea
methyl acetamido-2,6-anhydro-3,5-dideoxy-9-p-toluenesulfonyl-D-glycero-D-galactonon-2-enonate
2-(4-{[(3-fluorophenyl)amino]carbonothioyl}-1-piperazinyl)-8-ethyl-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid
2-tert-butoxycarbonylamino-3-(1H-indol-3-yl)-propionic acid 2-oxo-1,2-diphenyl-ethyl ester
[4-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-cyclohexyl]-carbamic acid tert-butyl ester
C22H25N5O6
2-Propenamide, N-(4-fluorophenyl)-
N-(3-chlorophenyl)-4-oxo-4H-chromene-2-carboxamide
1H-Indol-5-ol, 2,3-diphenyl-
4-(3-bromo-2-{2-[(2R)-2-methylpyrrolidin-1-yl]ethyl}-1-benzofuran-5-yl)benzonitrile
((1S,2R,3S,4R)-1-Benzyl-4-tert-butoxycarbonylamino-2,3-dihydroxy-5-phenyl-pentyl)-carbamic acid tert-butyl ester
C10H8BrF3N2O
2-(4-CHLORO-PHENYL)-4-METHYL-PYRIDINE
1,3-dichloro-2-{2-[4-(iodomethyl)phenoxy]ethoxy}-5-methylbenzene
Butanoic acid, 2-[bis[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-, methyl ester, (2S)-
[2-[4-(2-acetyl-phenyl)-piperazin-1-yl]-1-(4-chloro-benzyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
5-[ISOCYANO-(TOLUENE-4-SULFONYL)-METHYL]-BENZO[1,3]DIOXOLE
2-(2-phenyl-6,7-dihydrooxazolo[4,5-c]pyridin-5(4H)-yl)nicotinonitrile
(4-thien-2-yltetrahydropyran-4-yl)methylamine
3-AMINO-N-(4-METHOXY-PHENYL)-BENZENESULFONAMIDE
methyl 1-(4-fluorophenyl)-4-methyl-1,4-dihydropyrazolo[4,3-c][1,2]benzothiazine-3-carboxylate 5,5-dioxide
Benzenecarboximidamide, 4-(octyloxy)-
5-(4-aminophenyl)-1,6-naphthyridin-2(1H)-one
C17H13N3O3S
5-[[4-(2-oxo-2-phenylethoxy)phenyl]methyl]-2,4-thiazolidinedione
2-(1,3-thiazol-2-yl)acetonitrile
N-{3-benzyl-2-[4-fluoro-2-(1-hydroxyethyl)phenoxy]quinolin-6-yl}-(3-trifluoromethylphenyl)sulfonamide
4-(2-(5-(chloromethyl)-4-(4-(trifluoromethoxy)phenyl)-1H-1,2,3-triazol-1-yl)ethyl)-3,5-dimethylisoxazole
Acetic acid (3aS,4R,5S,6aR)-4-acetoxymethyl-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester
