Activating agent

A chemical (e.g., DCC, EDC, or oxalyl chloride) used to convert the carboxylic acid into a more reactive intermediate.

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Column chromatography Yield Solvent Mass spectrometry (MS) Nucleophilic substitution Deprotection TLC (thin-layer chromatography) HPLC (high-performance liquid chromatography) NMR (nuclear magnetic resonance) Weinreb amide Anhydrous conditions Carboxylic acid Peptide Synthesis Workup Solid-Phase Peptide Synthesis (SPPS) Coupling Reaction Quenching Orthogonal Protection Threonine Stoichiometry Side Reactions Purity serine Oxalyl chloride Fmoc (Fluorenylmethyloxycarbonyl) TFA (Trifluoroacetic Acid) IR Spectroscopy (Infrared Spectroscopy) DCC (Dicyclohexylcarbodiimide) Acyl chloride Resin (Solid Support) Side-chain protection

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