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Chemical Baike

Alkylation reaction

The Hantzsch 1,4-dihydropyridine is treated with an alkylating agent, such as an alkyl halide (e.g., methyl, ethyl, propyl, etc.) or an alkyl sulfate (e.g., methyl sulfate, ethyl sulfate, etc.). This reaction is typically carried out in the presence of a base, which facilitates the alkylation process.

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