LL-37 is known for its potent antimicrobial activity against a wide range of pathogens, including bacteria, fungi, and viruses. Cationic amphipathic peptides share structural and functional similarities with LL-37 and can serve as probes to understand the mechanisms behind LL-37's antimicrobial activity. By studying these analogs, researchers can gain insights into the specific structural features responsible for antimicrobial efficacy.
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