The solubility of a salt in water is influenced by the nature of the counterion. In general, alkali metal cations like sodium and potassium tend to enhance the solubility of a compound in water due to their ability to form ion-dipole interactions with water molecules. Therefore, the sodium and potassium salts of bumetanide trihydrate are likely to be more soluble in water than the parent compound.
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Benzoic acid, 3-(aminosulfonyl)-5-(butylamino)-4-phenoxy-, monopotassium salt
1,3,5-Triazin-2-amine, 4,6-dichloro-N,N-dicyclohexyl-
