Backbone Modification

Altering the core structure of a ligand.

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IR spectroscopy Elemental analysis Asymmetric synthesis Regioselectivity Flash chromatography Crystallization Yield NMR spectroscopy Distillation Enantioselective Ligand Hydrogenation Nucleophile Heck reaction Steric hindrance Enantiomeric excess (ee) Carbene Recrystallization Mass spectrometry (MS) Cross-coupling Cyclopropanation Deprotection Filtration GC (gas chromatography) Precursor Radical reaction Hydrogen bonding Microwave irradiation TLC (thin-layer chromatography) HPLC (high-performance liquid chromatography) coordination complex Epoxidation Intramolecular X-ray crystallography Leaving group Dielectric constant Chelation Diastereomers Inhibitor Metathesis Isomerization Ligand Design Asymmetric Induction Workup Chiral Resolution Oxidative Addition Reductive Elimination Electronic effects Organocatalysis Circular Dichroism (CD)

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