The resulting demethylxanthohumol is subjected to a base-catalyzed cyclization reaction. A strong base like sodium hydroxide (NaOH) is commonly used for this purpose. The base catalyzes the intramolecular cyclization of demethylxanthohumol, leading to the formation of flavanone or flavanonone compounds, depending on the specific reaction conditions.
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(+/-)-3,4,8,9-Tetrahydro-5-hydroxy-8-(4-hydroxyphenyl)-2,2-dimethyl-2H,10H-benzo<1,2-b:3,4-b'>dipyran-10-on
1,4-Dimethyl-5-phenethyl-1,2,5,6-tetrahydropyridin
