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Chemical Baike

Biological Significance

Fucosylation is a post-translational modification where fucose residues are added to glycan structures. The α-(1→4) and α-(1→8) fucosylation of sialic acid is crucial in the biosynthesis of certain gangliosides, especially those in the HPG-series. These gangliosides are known for their involvement in neuronal development, differentiation, and adhesion.

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