The choice of palladium catalyst and ligand can significantly influence the success of the reaction. The choice of ligand can impact the regioselectivity and reactivity. Experiment with different catalysts and ligands to optimize the reaction.
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1-(4-((5-(4-(difluoromethoxy)phenyl)pyrimidin-2-yl)-amino)benzyl)piperidine-4-carboxylic acid
cis-2-methyl 3-phenylthiocyanomethyl cyclohexanone
