Organic Process Research and Development p. 557 - 561 (2018)
Update date:2022-08-03
Topics: Characterization Reaction Conditions Reaction Mechanism Work-up and purification Iterative Optimization Catalyst and Ligand Selection
Wu, Quanbing
Xiong, Xin
Cao, Yudong
He, Lijuan
Fei, Zhongbo
Two convergent syntheses for compound 1 are described that apply Buchwald-Hartwig coupling as the key step. This development work provides a direct comparison of the coupling results from different coupling partners and illustrates that more efficiency ca
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