Chiral ligands are used in conjunction with the copper catalyst to impart enantioselectivity to the reaction. These ligands play a crucial role in controlling the facial selectivity of the nucleophilic addition, leading to the desired chiral product.
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(E)-1-Phenyl-hept-4-en-3-ol
(R)-3-((E)-Hept-1-enyl)-4-phenyl-oxazolidin-2-one
Benzenamine, 2-(diphenylphosphino)-N-methyl-
C28H28N6O2
(S)-4-methyl-4-phenyltetrahydro-2H-pyran-2-one
C17H18Cl2N6O
Triethyl orthoformate
Silica gel
Benzenemethanamine, a-butyl-, (R)-
(2R,5R)-1-(tert-butoxycarbonyl)-5-[(S)-methoxycarbonyl(4-bromophenyl)methyl]-2-[tert-butyldiphenylsilyloxymethyl]pyrrolidine
2,3-epoxycyclopentanone
(S)-1-benzenesulfonyl-4,5-bis(tert-butyldimethylsilyloxy)-1-diazo-2-pentanone
ethyl 3-(3-chlorophenyl)-2-diazo-3-hydroxypropanoate
3-cyclohexyl-N-pivaloylbutanamide
(E)-(R)-4-((R)-2,6,6-Trimethyl-cyclohex-2-enyl)-but-3-en-2-ol
(S)-1-phenyl-N-((pyrrol-2-yl)methyl)ethanamine
(1S,3R,4R)-3-(toluene-4-sulfonyloxymethyl)-2-azabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
(thiophen-2-yl)(4-(trifluoromethyl)phenyl)methanone
(1R,2S)-2-methoxy-1-phenyl-1-propanol
benzyl ((E)-2-((2S,4R)-6-methoxy-2-(naphthalen-2-yl)-1,2,3,4-tetrahydroquinolin-4-yl)vinyl)carbamate
(1aS,7S,7aS)-7-hydroxy-7,7a-dihydronaphtho[2,3-b]oxiren-2(1aH)-one
methyl 3-(4-trifluoromethylphenyl)-5-methyl-4,5-dihydroisoxazole-4-carboxylate
(S)-N,N-dibenzyl-2-fluoro-3-phenylpropan-1-amine
(S)-1-benzyl-2-(((3-chloropropyl)dimethylsilyloxy)diphenylmethyl)pyrrolidine
menthyl 2-phenylcyclopropanecarboxylate
4-methyl-4-(3-methyl-2-butenyl)-2-phenyl-2-oxazolin-5-one
(S)-ethyl 3-methyl-5-phenylpentanoate
4-chloro-N-(2,2-dimethylpent-4-enylcarbamoyl)benzenesulfonamide
(R)-1-(4-fluorophenyl)butane-1,4-diol
(S,S)-2,4-bis<(tert-butyldimethylsiloxy)methyl>-N-<(S)-1-phenylethyl>azetidine
bis(3-acetoxyphenyl)-2-pyridylmethane
