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Dihedral Angle

The angle between two intersecting planes in a molecule.

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Design and modular parallel synthesis of a MCR derived α-helix mimetic protein-protein interaction inhibitor scaffold
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- 5-[ISOCYANO-(TOLUENE-4-SULFONYL)-METHYL]-BENZO[1,3]DIOXOLE
Structure-based design of a highly constrained nucleic acid analogue: Improved duplex stabilization by restricting sugar pucker and torsion angle γ
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- C₂₅H₄₀O₆Si

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Synthesis Elemental analysis Asymmetric synthesis Enantiomer Regioselectivity Diastereoselectivity Green chemistry Residue Oligomer Solid-phase synthesis Lewis acid Column chromatography Characterization Melting point Crystallization Yield NMR spectroscopy Distillation Catalyst Cleavage Thin-layer chromatography (TLC) Selectivity Ligand Nucleophile Electrophile Molecular docking Solvent Stereochemistry Lead compound Infrared (IR) spectroscopy Enantioselectivity Deprotonation Chromatography Recrystallization Optimization Boiling point Protonation Mass spectrometry (MS) IC50 Differential scanning calorimetry (DSC) Atom economy Solubility Pharmacophore Potency Reagent Cyclization Scaffold Polymer Conformation binding affinity

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Dihedral Angle

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