Arylation involves the addition of an aryl group to a molecule. In the direct arylation step, an arylating agent is introduced to the reaction mixture, and the palladium catalyst facilitates the coupling of the aryl group with the other starting material (often the isoquinoline or its derivative).
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1-(2-bromoethyl)-2-phenylimidazole
norbornene
methyl 5-benzhydryl-2-methoxybenzoate
2-(2-methyl-5-nitrophenyl)-1H-pyrrole
4,4?-bis(2,4,6-triethylphenyl)-1,1′:4′,1″:4″,1?-quaternaphthalene
2-(2-iodophenyl)hexanoic acid
1-methyl-2-(2-methyl-4-nitrophenyl)-1H-pyrrole
