10.1002/chem.201703527
Chemistry - A European Journal
COMMUNICATION
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COMMUNICATION
Daniel Whitaker, María Batuecas, Paolo
Ricci and Igor Larrosa*
Page No. – Page No.
A Direct Arylation-Cyclization
Reaction for the Construction of
Medium-Sized Rings
An intermolecular cyclisation reaction has been developed, combining direct C–H
arylation with nucleophilic aromatic substitution. π-complexation of fluoroarenes to
Cr(CO)3 greatly enhances the reactivity of both steps. Rings with 6 to 10 members
are accessible through cyclisation with O, N and C-centered nucleophiles.
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