Enzyme-substrate complex

A temporary association between an enzyme and its substrate during catalysis.

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Inhibitors Selectivity Molecular docking Pharmacophore binding affinity Minimum inhibitory concentration (MIC) Hydrogen bonding X-ray crystallography Inhibitor Peptidomimetics Structure-Activity Relationship (SAR) Enzyme Kinetics Selective Inhibition Substrate Specificity Catalytic Activity tRNA (Transfer RNA) Cellular Uptake Kinetic Analysis Catalytic Mechanism Bacterial cell wall synthesis Active site Cell-based assay Biochemical assay Cofactor Antibiotic resistance Depsipeptides Peptidoglycan Gram-positive bacteria Serine protease Allosteric site IC50 (Half-Maximal Inhibitory Concentration) Ki (Inhibition constant) Histone Deacetylase (HDAC) Proteolytic cleavage

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