The reaction begins with the activation of an alkyne via coordination to the gold(I) catalyst. This generates a π-alkyne gold complex. A nearby nucleophilic amino group of 2-aminobenzylamine or its derivative attacks the alkyne, forming a pyrrole ring through a 5-endo-dig cyclization. This reaction leads to the formation of an intermediate with a pyrrole ring fused to a benzene ring.
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6-methyl-6-phenyl-5,6-dihydroindolo[1,2-a]quinoxaline
(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (4-methylphenyl)(oxo)acetate
6-chloro-8-(phenylethynyl) 2,3-dihydroquinolin-4(1H)-one
