Condensation of aldehyde, β-ketoester, and ammonia in the presence of a PTC catalyst. Common PTC catalysts include benzyltriethylammonium chloride or tetrabutylammonium bromide.
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2-[1-(4-chloro-phenyl)-3-oxo-propylidene]-malononitrile
(S)-2,6-Dimethyl-4-p-tolyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-tert-butyl ester 5-ethyl ester
4,4-Dimethyl-5-oxo-2-phenethyl-tetrahydro-furan-3-carboxylic acid ethyl ester
