Heteroannulation

Formation of a heterocyclic ring (containing at least one non-carbon atom) via cyclization.

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Regioselectivity Column chromatography Yield NMR spectroscopy Alkynes Ligand Schlenk techniques Optimization Mass spectrometry (MS) Cyclization Palladium-Catalyzed TLC (thin-layer chromatography) X-ray crystallography Workup Steric Effects Oxidative Addition Reductive Elimination Nucleophilic Attack Electronic effects Substrate Scope Stereoselectivity Catalyst Loading Reaction Monitoring Catalytic Cycle Nickel-Catalyzed Electrophilic Substitution Inert atmosphere 2-substituted-3-allylbenzo[b]furans Solvent Optimization π-Allyl Complex

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