HIV-1 protease

an enzyme produced by the human immunodeficiency virus (HIV) that is essential for the virus to replicate.

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Structure-based design and synthesis of HIV-1 protease inhibitors employing beta-D-mannopyranoside scaffolds.
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- methyl 3-O-benzyl-4,6-O-benzylidene-β-D-arabino-hexopyranosid-2-ulose
Potent HIV-1 Protease Inhibitors: Stereoselective Synthesis of a Dipeptide Mimic
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- (2S,4S,5S)-2,5-bis<<(1,1-dimethylethoxy)carbonyl>amino>-1,6-diphenyl-4-hydroxyhexane
Diastereo- and enantioselective synthesis of C₂-symmetrical HIV-1 protease inhibitors
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- ((1S,3S)-1-Benzyl-2-benzyloxy-3-tert-butoxycarbonylamino-4-phenyl-butyl)-carbamic acid tert-butyl ester

Synthesis Diastereoselectivity Inhibitors Enantioselectivity Stereoselective synthesis Stereoselective High-performance liquid chromatography (HPLC) Nuclear Magnetic Resonance (NMR) X-ray crystallography Symmetrical Structure-based design

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