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Chemical Baike

Imidazoles

Imidazoles are a class of organic compounds with a five-membered ring structure containing two nitrogen atoms. They are often used in medicinal chemistry to develop small molecule inhibitors of specific protein targets, such as kinases. In this case, the imidazoles are modified with various substituents (2-alkylsulfanyl, 4(5)-aryl, 5(4)-heteroaryl) to optimize their interaction with the ribose and phosphate binding site.

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Articles of Imidazoles

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