Journal of Organic Chemistry p. 3591 - 3594 (1987)
Update date:2022-09-26
Topics: Imidazoles Regiospecific Synthesis
Chivikas, Cleo J.
Hodges, John C.
A new strategy for regiospecific imidazole alkylation of suitably protected histidines is described wherein a phenacyl group serves as a protecting group of the distal imidazole nitrogen atom.Alkylation of N-BOC-1-phenacyl-L-histidine methyl ester at N(3)
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Doi:10.1021/ja00250a036
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