The McMurry coupling reaction involves the formation of a carbon-carbon double bond between two aryl (or alkyl) groups using a metal catalyst, typically a titanium-based catalyst. In the case of tri- and tetra-arylethylene analogues, multiple McMurry coupling reactions will be needed to connect the aryl rings and form the desired double bonds. The reaction is typically conducted under anhydrous conditions and often in an inert atmosphere to prevent interference from oxygen and moisture.
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2-{[3'-(tert-butyldimethylsilyl)oxy]-4'-methoxyphenyl}-1-phenyl-1-(3'',4'',5''-trimethoxyphenyl)-prop-1-ene
