Depending on the results of biological testing, further structural optimization may be required to enhance the potency and selectivity of the DNA inhibitors.
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6,10-dimethyl-1,4-bis(methoxycarbonyl)pyridazino[4,5-h]psoralen
n
5-(3,4-dimethoxybenzylidene)-2-(4-methylphenyl)-1,3-thiazol-4(5H)-one
(Z)-2-Bromomethyl-3-(3-chloro-phenyl)-acrylic acid ethyl ester
(2R)-2-bromo-4-methylpentanoic acid t-butyl ester
2-{[3'-(tert-butyldimethylsilyl)oxy]-4'-methoxyphenyl}-1-phenyl-1-(3'',4'',5''-trimethoxyphenyl)-prop-1-ene
5,6-bis[(acetyloxy)methyl]-7-oxabicyclo[2.2.1]hept-5-ene-2,3-diyl diacetate
1,2-Benzenediol, 4,4'-(1,3-propanediyl)bis-
(S)-4-[(R,E)-1-hydroxyhexadec-2-enyl]-3-(2-phenylacetyl)oxazolidin-2-one
