O-Methylation

Methylate the hydroxyl group at the 4-position using a methylating reagent, such as methyl iodide or methyl triflate.

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Synthesis of a potent aminocyclitol α-mannosidase inhibitor, 1L-(1,2,3,5/4)-5-amino-4-O-methyl-1,2,3,4-cyclopentanetetrol
Related Chemicals
- 1,2,3-Cyclopentanetriol,4-amino-5-(ethylthio)-,(1R,2R,3R,4S,5R)-(9CI)
Total synthesis of (±)-O-methylorantine
Related Chemicals
- (+/-)-O-methylorantine
Total synthesis of estrone via estriol dimethyl ether
Related Chemicals
- (+/-)-3-Methoxy-18-methylestra-1,3,5(10),8-tetraen-17β-ol

Oxidation Regioselectivity Characterization Yield NMR spectroscopy Reduction Chromatography Recrystallization Total synthesis Mass spectrometry (MS) Deprotection Protecting group Biological testing Intermediate Purification Starting Material Retrosynthetic analysis Reaction Conditions Grignard Reaction Starting Materials Stereoselectivity Catalysis Protection of Hydroxyl Groups Deprotection of Hydroxyl Groups Introduction of the Amino Group Steroid Purification techniques Characterization methods Estrone

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