UBRAs are designed to have unique physical properties that contribute to their ultrashort-acting nature. Lipophilicity and molecular weight are critical factors influencing a drug's ability to penetrate the blood-brain barrier. UBRAs are often designed to have optimal lipophilicity for rapid absorption and distribution to the central nervous system. Metabolism and elimination play a crucial role in determining the duration of action. UBRAs are often metabolized into inactive compounds, and their elimination half-life is relatively short, contributing to their ultrashort duration of action.
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(S)-3-(7-chloro-5-(2-fluorophenyl)-2-thioxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propionic acid methyl ester
6,8-bis(phenylthio)benzocycloheptene-1,4,7-trione
N-TERT-BUTYL-1 1-DIMETHYLPROPARGYLAMINE&
Phenol, 4-(9-anthracenyl)-2,6-bis(1,1-dimethylethyl)-
