Thyroliberin analogs are designed to retain the core structure of the natural thyroliberin molecule while introducing modifications to enhance stability, pharmacokinetics, and selectivity. Common modifications include the substitution of certain amino acids or the use of D-enantiomers.
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DL-Phenylalanine, N-(5-oxo-L-prolyl)-, 2-(3-carboxy-1-oxopropyl)hydrazide
Hydrazine
2-ethynyl-9,10-anthraquinone
β-Hydroxy-glutarsaeure-dibenzhydrylester
2,6-diphenyl-1,4-dithiine-1,1,4,4-tetraoxide
2-[2-Oxo-prop-(E)-ylidene]-1-phenyl-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one
Benzoyl chloride
Phenyl isocyanate
4,8-bis-(4-dodecylphenylethynyl)-2,6-dimethylbenzo[1,2-d-4,5-d']bisoxazole diethylphosphonate ester
FMOC-5-AMINOPENTANOIC ACID
(E)-3-(2-Bromo-phenyl)-acryloyl azide
2-(5-Bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene
(4-isobutylphenyl)acetonitrile
6,6'-(1,3,4-oxadiazole-2,5-diyl)bis(2-methylphenol)
2-(1H-benzimidazol-1-ylmethyl)-6-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
8-(2',3'-dihydroxypropyl)-8-phenylmethoxycarbonylamino-1,4-dioxaspiro[4.5]decane
3-(cyclohex-1-enyl)propyl acetate
2-CHLORO-N-PYRAZIN-2-YLACETAMIDE
[(2-amino-2-oxoethyl)thio]acetic acid(SALTDATA: FREE)
rac-<2R,3S(R)>-2-<3-<(chloroacetyl)oxy>-2-oxopropyl>-3-<1-<<(2,2,2-trichloroethoxy)carbonyl>oxy>ethyl>-4-oxo-α-(triphenylphosphoranylidene)azetidine-1-acetic acid (2,2-dimethyl-1-oxopropoxy)methyl ester
tert-Butyl-[(2R,3S)-3-(2-methoxy-ethoxymethoxy)-2-methyl-pent-4-enyloxy]-diphenyl-silane
Benzoic acid, 4-(3-oxo-1-pyrrolidinyl)-, methyl ester
(5Z)-5-(1H-INDOL-3-YLMETHYLENE)IMIDAZOLIDINE-2,4-DIONE
(E)-3-((1S,3R)-1-Benzyloxymethyl-3-hydroxy-4-methyl-pent-4-enyloxy)-acrylic acid ethyl ester
(3R,4R,5R)-3-benzoyloxy-4,5-dihydroxycyclohexanone 4,5-O-cyclohexylidene acetal
(1-Methyl-piperidin-4-yl)-(4-trifluoromethyl-phenyl)-amine
3-deoxyquinic acid
(S)-3-(7-chloro-5-(2-fluorophenyl)-2-thioxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propionic acid methyl ester
C24H22Cl2NPPd
1,3-bis([3,4,5-tris(benzyloxy)benzoyl]oxy)naphthalene
3-phenyl-6-chloro-2-pyranone
(E)-1-(3-azidophenyl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one
6-chloro-5-methyl-2-(piperazin-1-yl)-N-(propan-2-yl)pyrimidin-4-amine
2,4-Pyrrolidinedione, 5-ethyl-3-(1-hydroxyethylidene)-, [S-(Z)]- (9CI)
methyl 3,5-diisopropoxy-4-methoxybenzoate
2-bromo-1-(2-chloro-4-methoxyphenyl)-1-propanone
N,N'-(2,3-Naphthalenediyl)-1,2-benzoquinone diimine
(2R,5S)-2-(1-oxoethyl)-5-([(1,1-dimethyl)ethyldiphenylsilyl]oxymethyl)tetrahydrofuran
2,3,5-tri-O-benzyl-N',N'-bis-t-butyloxycarbonyl-4-O-trimethylsilyl-D-arabinonohydrazide
(E)-N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(3-fluoro-phenyl)-acrylamide
1,6-Di(cyclohexyl)-hexa-2,4-diin-1,6-diol
Norkokain
