What is spiroacetal

A cyclic compound in which three atoms are part of a spiro ring and one of the spiro atoms is an acetal group.

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A highly convergent total synthesis of the spiroacetal macrolide (+)-milbemycin β₁
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The chemistry of spiroacetals. An enantiospecific synthesis of the spiroacetal moiety of milbemycins α₇ and α₈
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Semi-synthetic C23-substituted milbemycins via spiroacetal cleavage and resynthesis
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Cleavage Stereoselectivity Convergent Synthesis Reaction Optimization Spectroscopic Analysis Semi-Synthetic Experimental conditions Macrolide Enantiospecific synthesis Milbemycins

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