In some cases, cyclodextrins can catalyze the electrophilic aromatic bromination by stabilizing transition states. The cavity of the cyclodextrin can interact with both the substrate and the brominating agent, potentially lowering the activation energy for the reaction.
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Acetanilide
Phenyl acetate
water
3-<
Benzoic acid, 3-(3-oxopropyl)-
2-(p-fluorobenzoyl)adamantane
