Terminal phenylthio group

Functionalization Lysergic acid Ergot alkaloids Radical cyclisation Tri-n-butyltin hydride Indolyl unit Annulation reactions LDA AcCl HF MnO2 Ph3P=CH(OMe) 13X mol. sieves Purification and characterization Safety and Regulatory Considerations Radical Cyclization Start with a suitable precursor Generate radical intermediates