Utilize transition metal-catalyzed cross-coupling reactions, such as Suzuki-Miyaura coupling or Stille coupling, to introduce the desired alkyl group. Palladium or nickel catalysts can facilitate these reactions. This method can be advantageous in terms of selectivity and mild reaction conditions.
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tert-butyl 6'-benzyl-N-tert-butyl-7'-oxo-6',7'-dihydro-2'H-spiro[piperidine-4,5'-pyrano[3,2-c]pyrazole]-1-carboxylate
2-Benzoxazoleacetic acid, ethyl ester
