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Name Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (αR)-
EINECSN/A
CAS No. 1334321-39-9
Density1.296±0.06 g/cm3 (20 oC 760 Torr)
PSA95.86000
LogP2.68650
Solubility(0.27 g/L) (25 oC)
Melting PointN/A
FormulaC17H27NO5
Boiling Point497.3±20.0 °C(Predicted)
Molecular Weight325.405
Flash PointN/A
Transport InformationN/A
AppearanceWhite powder
Safety
Risk CodesN/A
Molecular Structure
Hazard SymbolsN/A
SynonymsN/A
Article Data3

Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (αR)- Specification

Boc-3-hydroxy-1-adamantyl-L-glycine is an impurity of Saxagliptin (S143500), which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.

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Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (αR)-

Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (αR)- Specification

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