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Trimeprazine

  • Name Trimeprazine
  • EINECS201-577-3
  • CAS No. 84-96-8
  • Density1.203 g/cm3
  • PSA31.78000
  • LogP4.55200
  • Solubility0.942 mg/L in water
  • Melting Point68 ºC
  • FormulaC18H22 N2 S
  • Boiling Point420.3°Cat760mmHg
  • Molecular Weight298.452
  • Flash Point208°C
  • Transport InformationN/A
  • AppearanceLight Yellow Solid
  • SafetyPoison by ingestion and intravenous routes. When heated to decomposition it emits very toxic fumes of NOx and SOx.
  • Risk CodesR20/21/22; R36/37/38
  • Molecular Structure
    Molecular Structure of 84-96-8 (Trimeprazine)
  • Hazard SymbolsXn
  • SynonymsXn
  • Article Data6

Trimeprazine Chemical Properties

Product Name: Alimemazine (CAS NO.84-96-8)


Molecular Formula: C18H22N2S
Molecular Weight: 298.45g/mol
Mol File: 84-96-8.mol
Einecs: 201-577-3
Melting Point: 68°C
Boiling point: 420.3 °C at 760 mmHg
Flash Point: 208 °C
Density: 1.114 g/cm3
Water Solubility: 0.942 mg/L
Surface Tension: 43.4 dyne/cm
Enthalpy of Vaporization: 67.41 kJ/mol
Vapour Pressure: 2.84E-07 mmHg at 25°C
XLogP3: 4.7
H-Bond Donor: 0
H-Bond Acceptor: 2

Trimeprazine Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 33mg/kg (33mg/kg)   Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963.
mouse LD50 oral 300mg/kg (300mg/kg) BEHAVIORAL: ANTIPSYCHOTIC Developments in Neuroscience Vol. 7, Pg. 45, 1980.
mouse LD50 subcutaneous 300mg/kg (300mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967.
rat LD50 intravenous 35mg/kg (35mg/kg)   Acta Neurologia et Psychiatrica Belgica. Vol. 61, Pg. 669, 1961.
rat LD50 oral 210mg/kg (210mg/kg)   Acta Neurologia et Psychiatrica Belgica. Vol. 61, Pg. 669, 1961.

Trimeprazine Safety Profile

Poison by ingestion and intravenous routes. When heated to decomposition it emits very toxic fumes of NOx and SOx.

Trimeprazine Specification

 Alimemazine ,its CAS NO. is 84-96-8,the synonyms is n,n,2-Trimethyl-3-phenothiazin-10-yl-propan-1-amine ; Trimeprazine ; alimemazine ; 10-[2-Methyl-3-(dimethylamino)propyl]phenothiazine ; 10-[3-(Dimethylamino)-2-methylpropyl]phenothiazine ; 10H-Phenothiazine-10-propanamine, N,N,beta-trimethyl- ; Alimezine ; Bayer 1219 .

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