IUPAC Name: 2,5,9-Trimethylfuro[3,2-g]chromen-7-one
Synonyms:2 ,5,9-Trimethyl-7H-furo[3,2-g][1]benzopyran-7-one ; 2,5,9-Trimethyl-7H-furo[3,2-g]chromen-7-one ; 6-Hydroxy-b,2,7-trimethyl-5-benzofuranacrylic Acid d-Lactone ; 7H-Furo(3,2-g)(1)benzopyran-7-one, 2,5,9-trimethyl-
CAS NO: 3902-71-4
Molecular Formula of 6-Hydroxy-β,2,7-trimethyl-5-benzofuranacrylic acid γ-lactone (CAS NO.3902-71-4) : C₁₄H₁₂O₃
Molecular Weight of 6-Hydroxy-β,2,7-trimethyl-5-benzofuranacrylic acid γ-lactone (CAS NO.3902-71-4) : 228.24
Molecular structure of 6-Hydroxy-β,2,7-trimethyl-5-benzofuranacrylic acid γ-lactone (CAS NO.3902-71-4) :
EINECS: 223-459-0
Index of Refraction: 1.613
Surface Tension: 45.2 dyne/cm
Density: 1.236 g/cm³
Flash Point: 189.1 °C
Enthalpy of Vaporization: 63.83 kJ/mol
Boiling Point: 389 °C at 760 mmHg
Vapour Pressure: 2.93E-06 mmHg at 25°C
Melting point: 229-231 °C(lit.)
Storage temp: 2-8°C
Solubility: DMSO: soluble
Appearance:White to slightly beige crystalline powder

 6-Hydroxy-β,2,7-trimethyl-5-benzofuranacrylic acid γ-lactone (CAS NO.3902-71-4) is a furanocoumarin and a psoralen derivative.

Raw materials :Etanol-->Sodium hydroxide-->Methanol-->Potassium carbonate-->Magnesium sulfate-->Acetone-->Ethyl acetoacetate-->Sulfamic acid -->N,N-Diethylaniline-->Potassium bisulfate -->1,2,3-Tribromopropane-->2-Methylresorcinol
It is obtained from several plants, mainly Psoralea corylifolia.

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 366.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 40 , 1986,p. 357.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 40 , 1986,p. 357.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory.

Moderately toxic by intraperitoneal and subcutaneous routes. Low toxicity by ingestion. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors.
Hazard CodesC
Risk Statements 34-40
R34:Causes burns. 
R40:Limited evidence of a carcinogenic effect.
Safety Statements 26-36/37/39-45
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR UN 1759 8/PG 1
WGK Germany 2
RTECS LV1576000
F 8-10

Like other psoralens it causes photosensitization of the skin. It is administered either topically or orally in conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of vitiligo and hand eczema.After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death unless repaired by cellular mechanisms. In research it can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage.The compound is also being explored for development of antisense oligonucleotides that can be cross-linked specifically to a mutant mRNA sequence without affecting normal transcripts differing at even a single base pair.