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Tylosin hydrochloride

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Name

Tylosin hydrochloride

EINECS N/A
CAS No. 11032-12-5 Density N/A
PSA 238.67000 LogP 2.63550
Solubility N/A Melting Point 128-132oC
Formula C46H77 N O17 . Cl H Boiling Point 980.7°C at 760 mmHg
Molecular Weight 940.69 Flash Point 546.9°C
Transport Information N/A Appearance N/A
Safety Poison by intravenous route. When heated to decomposition it emits very toxic fumes of NOx and HCl. Risk Codes N/A
Molecular Structure Molecular Structure of 11032-12-5 (L-Tyrosine·hydrochloride) Hazard Symbols 3
Synonyms

Oxacyclohexadecane,tylosin deriv.

 

Tylosin hydrochloride Chemical Properties

IUPAC Name: 2-[(1R,3R,5E,7E,10R,14R,16S)-16-[(2R,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-10-ethyl-14-hydroxy-9-[[(3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-3,7,15-trimethyl-4,12-dioxo-11-oxacyclohexadeca-5,7-dien-1-yl]acetaldehyde hydrochloride
Synonyms of Tylosin hydrochloride (CAS NO.11032-12-5) : Tylosin, hydrochloride
InChI:InChI=1/C46H77NO17.ClH/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;1H/b15-14+,23-18+;/t24-,25?,26-,27-,28+,29+,30?,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45?,46-;/m1./s1
CAS NO:11032-12-5
Molecular Formula:C46H78ClNO17
Molecular Weight :952.561
Molecular Structure :
Flash Point: 546.9 °C
Enthalpy of Vaporization: 162.01 kJ/mol
Boiling Point: 980.7 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25°C
 

Tylosin hydrochloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intravenous 4mg/kg (4mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Food and Cosmetics Toxicology. Vol. 4, Pg. 1, 1966.
mouse LD50 intravenous 582mg/kg (582mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Food and Cosmetics Toxicology. Vol. 4, Pg. 1, 1966.

Tylosin hydrochloride Safety Profile

Poison by intravenous route. When Tylosin hydrochloride (CAS NO.11032-12-5) is heated to decomposition ,it emits very toxic fumes of NOx and HCl.

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