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Tyloxapol

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Name

Tyloxapol

EINECS N/A
CAS No. 25301-02-4 Density 1.1
PSA 49.83000 LogP 4.57360
Solubility N/A Melting Point N/A
Formula (C14H22O•C2H4O•CH2O)x Boiling Point 282.3°C at 760 mmHg
Molecular Weight 137.17904 Flash Point 113 °C
Transport Information N/A Appearance Clear light yellow viscous liquid
Safety 26-36 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 25301-02-4 (Tyloxapol) Hazard Symbols Xi
Synonyms

formaldehyde; oxirane; 4-(2,4,4-trimethylpentan-2-yl)phenol;Superiuone;Alevaire;component of Alevaire;Formaldehyde, polymer with oxirane and 4- (1,1,3,3-tetra methylbutyl)phenol;AleuroneAleutian mink disease virusAlevaire;Formaldehyde,polymers,polymer with oxirane and 4-(1,1,3,3-tetramethylbutyl)phenol;Phenol, p- (1,1,3,3-tetramethylbutyl)-, polymer with ethylene oxide and formaldehyde;Tyloxypal;Triton WR 1339;Triton WR-1339;Triton A-20;Superinone;

 

Tyloxapol Chemical Properties

   The molecular formula of p-(1,1,3,3-TETRAMETHYLBUTYL)PHENOL, polymer with ETHYLENE OXIDE and FORMALDEHYDE(25301-02-4) is (C14H22O.C2H4O.CH2O)n and its formula weight is (280.4024)n g/mol.The appearance of  p-(1,1,3,3-TETRAMETHYLBUTYL)PHENOL, polymer with ETHYLENE OXIDE and FORMALDEHYDE(25301-02-4)  is clear light yellow viscous liquid.The density of p-(1,1,3,3-TETRAMETHYLBUTYL)PHENOL, polymer with ETHYLENE OXIDE and FORMALDEHYDE(25301-02-4) is 1.1g/cm3.The boiling point is 282.3 °C at 760 mmHg.Enthalpy of vaporization is 54.21 kJ/mol.Its flash point is 148.3 °C and the vapor pressure is 0.00198 mmHg at 25°C. p-(1,1,3,3-TETRAMETHYLBUTYL)PHENOL, polymer with ETHYLENE OXIDE and FORMALDEHYDE(25301-02-4)  has the property of being dissolved in benzene, toluene, chloroform, carbon tetrachloride, carbon disulfide and acetic acid.
   The chemical synonyms of  p-(1,1,3,3-TETRAMETHYLBUTYL)PHENOL, polymer with ETHYLENE OXIDE and FORMALDEHYDE(25301-02-4) are ETHOXYLATED P-TERT-OCTYLPHENOL FORMALDEHYDE POLYMER;4-(1,1,3,3-TETRAMETHYLBUTYL)PHENOL POLYMER WITH FORMALDEHYDE AND OXIRANE;TYLOXAPOL;TRITON(R) WR-1339;4-(1,1,3,3-tetramethylbutyl)-phenopolymerwithformaldehydeandoxirane;alevaire;formaldehyde,polymerwithoxiraneand4-(1,1,3,3-tetramethylbutyl)phenol;macrocyclon;oxyethylatedtertiaryoctyl-phenol-formaldehydepolymer;p-(1,1,3,3-tetramethylbutyl)phenolpolymerwithethyleneoxideandformaldehy;p-(1,1,3,3-tetramethylbutyl)-phenopolymerwithethyleneoxideandformalde;p-isooctylpolyoxyethylenephenolformaldehydepolymer;superinone;superiuone;tritona-20;tritonwr1339;tyloxypal;TYLOXAPOL SIGMAULTRA;TYLOXAPOL REAGENT GRADE and 4-(1,1,3,3,-Tetramethyl buthyl)phenol (Tloxapol), etc.The molecular structure of p-(1,1,3,3-TETRAMETHYLBUTYL)PHENOL, polymer with ETHYLENE OXIDE and FORMALDEHYDE(25301-02-4)  is .

Tyloxapol Toxicity Data With Reference

1.   

ivn-rat TDLo:1 g/kg (10D preg):TER

   PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 122 (1966),874.
2.   

ipr-mus TDLo:600 mg/kg (6-8D preg):REP

   CHDDAT    Comptes Rendus Hebdomadaires des Seances de l’Academie des Sciences, Serie D. 266 (1968),2171.
3.   

ivn-rat LD50:1800 mg/kg

   NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),467.
It is irritating to eyes, respiratory system and skin.May cause sensitisation by skin contact.

Tyloxapol Safety Profile

Moderately toxic by intravenous route. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes. Risk codes is 36/37/38 43.
Hazard symbols is Xi.
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