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1143-38-0

Basic Information
CAS No.: 1143-38-0
Name: ANTHRALIN
Article Data: 29
Molecular Structure:
Molecular Structure of 1143-38-0 (ANTHRALIN)
Formula: C14H10O3
Molecular Weight: 226.232
Synonyms: Anthrone,1,8-dihydroxy- (6CI,7CI,8CI);1,8-Dihydroxy-9-anthrone;1,8-Dihydroxyanthrone;Anthra-Derm;Batidrol;Batridol;Chrysodermol;Cignolin;Cigthranol;Derobin;Dithranol;DrithoCreme;Drithoscalp;Lasan;NSC 43970;NSC 629313;Psodadrate;Psoriacid-Stift;Psoriacide;
EINECS: 214-538-0
Density: 1.419 g/cm3
Melting Point: 178-181 °C(lit.)
Boiling Point: 464.1 °C at 760 mmHg
Flash Point: 248.6 °C
Solubility: <0.1 g/100 mL at 20 °C in water
Appearance: yellow crystalline solid
Hazard Symbols: IrritantXi,ToxicT
Risk Codes: 36/37/38-45
Safety: 26-53-45
PSA: 57.53000
LogP: 2.23300
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  • Best price/1,8-Dihydroxy-anthrone  CAS NO.1143-38-0

  • Casno:

    1143-38-0

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Chemistry

Chemical Name: Anthralin
IUPAC NAME: 1,8-Dihydroxy-10H-anthracen-9-one
CAS No.: 1143-38-0
EINECS: 214-538-0
RTECS: CB8927000
Molecular Formula: C14H10O3
Molecular Weight: 226.23 g/mol
Melting Point: 178-181 °C(lit.)
Density: 1.419 g/cm3 
Flash Point: 248.6 °C
Boiling Point: 464.1 °C at 760 mmHg
Following is the structure of Dithranol (1143-38-0):


Product Categories about Dithranol (1143-38-0) are Aromatic Phenols ; Intermediates & Fine Chemicals ; Pharmaceuticals
The chemical synonymous of Dithranol (1143-38-0) are Dithranol ; Dithranol, anthralin ; Anthralin ; 1,8-Dihydroxy-10h-anthracen-9-one ; 1,8-Dihydroxy-9(10h)-anthracenone ; 1,8-Dihydroxyanthrone ; 1,8,9-Anthracenetriol ; 1,8-Dihydroxy-9(10h)-anthracenon

Uses

The major use of Dithranol is as an treatment for psoriasis,it also used as a dermatology medication.

Toxicity Data With Reference

1.    

skn-hmn 0.1%/20M MLD

    ADVEA4    Acta Dermato-Venereologica. 67 (1987),72.
2.    

skn-hmn 0.05%/12H

    ADVEA4    Acta Dermato-Venereologica. 18 (1988),117.
3.    

skn-hmn 0.1%/1H MLD

    ADVEA4    Acta Dermato-Venereologica. 67 (1987),72.
4.    

skn-hmn 0.0025%/24H MLD

    ADVEA4    Acta Dermato-Venereologica. 63 (1983),513.
5.    

skn-hmn 0.01%/24H open

    ADVEA4    Acta Dermato-Venereologica. 173 (1986),288.
6.    

skn-hmn 0.02%/48H MOD

    ADVEA4    Acta Dermato-Venereologica. 93 (1989),695.

Safety Profile

A mild skin irritant. When heated to decomposition it emits acrid smoke and irritating vapors.
Hazard Codes:
Xi: Irritant
T: Toxic
Risk Statements about Dithranol (1143-38-0):
R45 May cause cancer.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements about Dithranol (1143-38-0):
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S53 Avoid exposure - obtain special instructions before use.