Products Categories
| CAS No.: | 117-10-2 |
|---|---|
| Name: | 1,8-Dihydroxyanthraquinone |
| Molecular Structure: | |
|
|
|
| Formula: | C14H8O4 |
| Molecular Weight: | 240.215 |
| Synonyms: | Anthraquinone,1,8-dihydroxy- (8CI);1,8-Dihydroxy-9,10-anthracenedione;1,8-Dihydroxy-9,10-anthraquinone;1,8-Dioxyanthraquinone;Antrapurol;Chrysazin;Danthron;Danthrone;Diaquone;Laxanorm;Laxanthreen; |
| EINECS: | 204-173-5 |
| Density: | 1.541 g/cm3 |
| Melting Point: | 191-193 °C |
| Boiling Point: | 452.667 °C at 760 mmHg |
| Flash Point: | 241.691 °C |
| Solubility: | insoluble in water |
| Appearance: | orange-brown or brown powder |
| Hazard Symbols: |
 Xn
|
| Risk Codes: | 40 |
| Safety: | 36/37-22 |
| PSA: | 74.60000 |
| LogP: | 1.87320 |
- 144851-82-1METHYL2-AMINO-3-FLUOROBENZOATE
- 483366-12-7(2S,4R)-1-Boc-2-cyano-4-hydroxypyrrolidine
- 173606-50-3BOC-10-AMINODECANOIC ACID
- 361456-36-2METHYL (R)-(+)-ISOCYANATO-3-PHENYLPROPI&
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 1219080-61-1IMIDAZOLE-2-BORONIC ACID
| Conditions | Yield |
|---|---|
| With water; trifluoroacetic acid at 65℃; for 1h; | 100% |
- 69043-83-0
1,4-dioxo-1,2,3,4-tetrahydro-5,9,10-trihydroxyanthracene(leuco 1,4,5-trihydroxy-9,10-anthraquinone)
A
- 117-12-4
1,5-dihydroxyanthraquinone
B
- 117-10-2
1,8-dihydroxy-9,10-anthracenedione
| Conditions | Yield |
|---|---|
| With pyrrolidine In toluene for 1.5h; Heating; | A 93% B n/a |
- 1432067-68-9
1,8-bis(2-phenylselenoethoxy)anthracene-9,10-dione
A
- 117-10-2
1,8-dihydroxy-9,10-anthracenedione
B
- 1432067-84-9
1-hydroxy-8-(2-phenylselenoethoxy)anthracene-9,10-dione
| Conditions | Yield |
|---|---|
| With iron (III) perchlorate monohydrate In dichloromethane for 2h; | A n/a B 90% |
| With copper(II) perchlorate hexahydrate In dichloromethane for 2h; | A n/a B 70% |
- 577975-52-1
4-hydroxy-10-imino-5-methoxymethoxy-10H-anthracen-9-one
- 117-10-2
1,8-dihydroxy-9,10-anthracenedione
| Conditions | Yield |
|---|---|
| With sulfuric acid In 1,4-dioxane; methanol at 20℃; for 96h; | 86% |
- 1182282-39-8
1,8-bis(prop-2-ynyloxy)anthracene-9,10-dione
A
- 117-10-2
1,8-dihydroxy-9,10-anthracenedione
| Conditions | Yield |
|---|---|
| With iron at 160℃; for 0.0666667h; Claisen Rearrangement; Ionic liquid; | A 16% B 73% |
- 1393091-17-2
1-hydroxy-8-(prop-2'-ynyloxy)anthraquinone
A
- 117-10-2
1,8-dihydroxy-9,10-anthracenedione
| Conditions | Yield |
|---|---|
| With iron at 160℃; for 0.2h; Claisen Rearrangement; Ionic liquid; | A 15% B 73% |
- 84399-87-1
8-Hydroxy-1,1,4-trimethoxy-1,4,4a,9a-tetrahydro-anthraquinone
- 117-10-2
1,8-dihydroxy-9,10-anthracenedione
| Conditions | Yield |
|---|---|
| With sulfuric acid | 67% |
- 78526-20-2
1,1-ethylenedioxy-6-hydroxy-1,4,4α,9aα-tetrahydro-9,10-anthraquinone
- 117-10-2
1,8-dihydroxy-9,10-anthracenedione
| Conditions | Yield |
|---|---|
| With acetic acid at 100℃; for 0.333333h; | 40% |
- 89646-25-3
3-Hydroxy-2-(2-hydroxybenzoyl)-benzoesaeure
- 117-10-2
1,8-dihydroxy-9,10-anthracenedione
| Conditions | Yield |
|---|---|
| With sulfuric acid; sulfur trioxide; boric acid at 120℃; for 0.5h; | 38.4% |
| With boron trioxide; sulfuric acid at 100℃; |
A
- 117-10-2
1,8-dihydroxy-9,10-anthracenedione
| Conditions | Yield |
|---|---|
| With sodium acetate; pyridinium chlorochromate In dichloromethane at 20℃; for 26h; Inert atmosphere; | A n/a B 34% |
- 1171197-20-8(S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate
- 117259-24-21-Aminocyclobutanecarboxylic acid
- 117342-26-4Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one,2'-bromo-6'-(dibutylamino)-3'-methyl-
- 117382-22-61-bromo-1,1,2,2-tetrafluoro-2-(1,2,2,2-tetrafluoroethoxy)ethane
- 117-39-5Quercetin
- 117581-13-21,4-Benzenedicarboxylic acid, polymer with 1,3-dihydro-1,3-dioxo-5-isobenzofurancarboxylic acid,dihydro-3-(tetrapropeny)-2,5-furandione, alpha,alpha′-[(1-methylethylidene)di-4,1-phenylene]bis[omega-hydroxypoly[oxy(methyl-1,2-ethanediyl)]and alpha,alpha′-[
- 1176-03-0[1R-(2-endo,3-exo)]-3-(benzoyloxy)-2-(methoxycarbonyl)-8-methyl-8-azoniabicyclo[3.2.1]octane hydrogen [R-(R*,R*)]-tartrate
- 117-62-42-Amino-1,5-naphthalenedisulfonic acid
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
What can I do for you?
Get Best Price
Uses
The major use of 1,8-Dihydroxyanthraquinone (117-10-2) is as an intermediate in the production of alizarin and indanthrene dyestuffs.
Consensus Reports
NTP 10th Report on Carcinogens. Reported in EPA TSCA Inventory.
Specification
The 1,8-Dihydroxyanthraquinone, with the CAS registry number 117-10-2, is also known as 1,8-Dihydroxy-9,10-anthraquinone. It belongs to the product categories of Intermediates of Dyes and Pigments; Anthraquinones; Hydroxyanthraquinones; Aromatics; Intermediates & Fine Chemicals; Pharmaceuticals. Its EINECS registry number is 204-173-5. This chemical's molecular formula is C14H8O4 and molecular weight is 240.21. What's more, its IUPAC name is called 1,8-Dihydroxyanthracene-9,10-dione. It should be stored in a cool, dry and well-ventilated place.
Physical properties about 1,8-Dihydroxyanthraquinone are: (1)ACD/LogP: 4.003; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 3.93; (4)ACD/LogD (pH 7.4): 2.43; (5)ACD/BCF (pH 5.5): 551.84; (6)ACD/BCF (pH 7.4): 17.35; (7)ACD/KOC (pH 5.5): 3049.70; (8)ACD/KOC (pH 7.4): 95.86; (9)#H bond acceptors: 4; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 74.6 Å2; (13)Index of Refraction: 1.733; (14)Molar Refractivity: 62.432 cm3; (15)Molar Volume: 155.926 cm3; (16)Polarizability: 24.75×10-24cm3; (17)Surface Tension: 79.282dyne/cm; (18)Density: 1.541 g/cm3; (19)Flash Point: 241.691 °C; (20)Enthalpy of Vaporization: 73.928 kJ/mol; (21)Boiling Point: 452.667 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25 °C.
Preparation of 1,8-Dihydroxyanthraquinone: this chemical can be prepared by 3-hydroxy-2-salicyloyl-benzoic acid. This reaction needs reagent H2SO4 at temperature of 120 °C. The reaction time is 30 min. The yield is 38.4 %.
Uses of 1,8-Dihydroxyanthraquinone: (1) it is used as a stimulant laxative and used as intermediates in the production of alizarin and indanthrene dyestuffs; (2) it is used to produce other chemicals. For example, it can react with sulfuric acid dimethyl ester to get 1,8-dimethoxy-anthraquinone. The reaction occurs with reagent K2CO3 and other condition of heating for 48 hours. The yield is 77 %.
When you are dealing with this chemical, you should be very careful. This chemical may cause damage to health and it has limited evidence of a carcinogenic effect. Therefore, you should wear suitable protective clothing and gloves.
You can still convert the following datas into molecular structure:
(1) SMILES: c1cc2c(c(c1)O)C(=O)c3c(cccc3O)C2=O
(2) InChI: InChI=1S/C14H8O4/c15-9-5-1-3-7-11(9)14(18)12-8(13(7)17)4-2-6-10(12)16/h1-6,15-16H
(3) InChIKey: QBPFLULOKWLNNW-UHFFFAOYSA-N
The toxicity data is as follows:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 500mg/kg (500mg/kg) | National Technical Information Service. Vol. AD277-689, | |
| mouse | LD50 | intravenous | > 10gm/kg (10000mg/kg) | Pharmacology and Toxicology Vol. 61, Pg. 153, 1987. | |
| mouse | LD50 | oral | > 7gm/kg (7000mg/kg) | Drug and Chemical Toxicology. Vol. 1, Pg. 89, 1977/1978. | |
| rat | LD50 | intraperitoneal | 1110mg/kg (1110mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 52(12), Pg. 93, 1987. |